top of page
chemrules.tif

Rewriting The Future of Medicine by Design

Empowering tomorrow's cures through

zero-shot drug design

Targeting the most challenging diseases

First Atom's Pipeline of PRISM Platform™ Designed, Disease-Modifying Therapeutics

Disease Areas

First Atom Therapeutics has successfully designed breakthrough therapeutics for diseases with high unmet medical need, including Amyotrophic Lateral Sclerosis, hereditary optic atrophies, and Parkinson's Disease, using First Atom's proprietary PRISM Platform™. Learn more about our pipeline medicines and active discovery programs.

Leveraging a Revolutionary Drug Design Technology Towards Changing Patient Outcomes

15+

New Chemical Entity Programs Designed

20+

Scientific

Collaborations

2

IND-stage Medicines aimed for clinic

5+

Drug Optimization

Projects

Strategic
Collaboration & Transformative Partnerships

Mayo
ALS Association
BCH
Advancium
Harvard
Nvidia
Abbvie
CMT

The PRISM Design Platform - Tailored Design
of New Medicines 

Protein

PRISM Platform™ is a revolutionary drug design technology that leverages zero-shot AI-integration for the atom-by-atom de novo design of new medicines. The PRISM Platform™ does not utilize any existing chemical structures for the development of new medicines. Instead, the PRISM Platform™ uses proprietary algorithms to enable the rational design of target specific compounds.

 

  

Dependent on existing compound libraries

Throughput-driven

Serendipitous

Misses cryptic pockets

10   compounds accessed

through screening

9

Constructs molecules from first principles

Insight-driven

Deterministic

Reveals latent structure

10    compounds accessed

through design

63

Design vs. Screening

Drug Screening Methods

PRISM Platform™ De Novo Design

bottom of page